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Introduction
Anorexia nervosa is a serious, potentially life-threatening eating disorder characterized by self-starvation and excessive weight loss (Anorexia Nervosa, 2022). Sufferers of anorexia have a distorted body image where they see themselves as overweight despite being underweight. Their self-esteem is heavily dependent on controlling their weight and shape, resulting in an intense fear of gaining weight. This paper will examine anorexia nervosa through a comprehensive literature review, covering topics such as causes and risk factors, symptoms and health consequences, treatment options, and prevention strategies.

Causes and Risk Factors
While the exact causes of anorexia are unknown, research indicates that genetics, biological factors, personality traits, and sociocultural pressures can all play a role (Bulik et al., 2007). Individuals with a family history of eating disorders, affective disorders, or obsessive-compulsive disorder are at higher risk. The heritability of anorexia is estimated between 50-80% (Fairburn & Harrison, 2003). Biological abnormalities linked to anorexia include alterations in neurotransmitters like serotonin which regulate appetite and mood. Personality traits common among anorexics include perfectionism, anxiety, impulsivity, low self-esteem and a need for control.

Sociocultural pressures also greatly influence risk through the promotion of thin-ideal images, especially in western cultures. Exposure to media portraying ultra-thin celebrities and models increases body dissatisfaction, a known risk factor for eating disorders (Groesz et al., 2002). Early life experiences like trauma, abuse, bullying or overly critical parenting have been correlated with disordered eating and poor body image (Preti et al., 2009). Other risks include strict dieting, extreme exercise, peer pressure, transitional life changes and co-occurring mental health issues like depression. Females represent 85-90% of clinical cases, with onset most prevalent in adolescence and early adulthood.

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Symptoms and Health Consequences
The three main diagnostic criteria for anorexia includes restriction of energy intake leading to significantly low body weight, intense fear of gaining weight or becoming fat, and a disturbance in self-perceived weight or body shape (American Psychiatric Association, 2013). Physical symptoms include dramatic weight loss, menstrual irregularities, lanugo hair growth, dry skin, fatigue, dizziness, constipation and lanugo hair growth. Physiological complications arise from prolonged calorie deprivation and include arrhythmias, hypotension, electrolyte imbalances, anemia, osteoporosis, muscle wasting and cardiac issues.

Long term consequences can range from growth retardation in teens to early bone loss, infertility, kidney damage, intestinal ruptures, cardiac arrest and risk of suicide if untreated. Mortality rates in anorexia are 12 times higher than the general population, with suicide, medical complications and starvation cited as main causes of death (Papadopoulos et al., 2009). Co-occurrence of other mental disorders like depression, anxiety, OCD and substance abuse are also common, exacerbating treatment challenges. Anorexia has the highest mortality rate of any mental illness but can be successfully treated if caught early.

Treatment Options
A multi-disciplinary approach is recommended for managing anorexia which often requires long term care. Treatment modalities may include outpatient psychotherapy, partial hospitalization programs, residential or intensive inpatient care depending on medical stability and symptom severity. The core psychotherapies are cognitive behavioral therapy (CBT), interpersonal therapy (IPT) and family-based therapy for adolescents. CBT focuses on identifying and altering dysfunctional thoughts, emotions and behaviors related to body image, eating and weight (Fairburn et al., 2009). IPT focuses on improving interpersonal difficulties and relationships that often coincide with or trigger onset of anorexia.

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Family-based approaches involve parents/caregivers learning to take control over eating and meal planning to promote healthy weight restoration in teens. Medical treatment may include prescription medication, nutritional counseling, diet plans, supplements to correct electrolyte imbalances and weight restoration. Hospitalization is required if patients are medically unstable or refuse to eat, requiring naso-gastric tube feeding or intravenous hydration. Completely recovering from anorexia takes 1-3 years on average, requiring ongoing therapy to maintain behavioral changes and prevent relapse which occurs in 20-30% of cases (Keel & Brown, 2010). Prognosis depends on early intervention, psychosocial support systems, personality traits and comorbid conditions.

Prevention Strategies
A public health, multi-level approach is needed to address the complex sociocultural and biological factors driving the occurrence of eating disorders. Public education promoting body positivity, health at every size, and evidence-based messages on media literacy can help reduce internalization of unrealistic thin ideals, especially for young girls and women. Regulating photoshopping and promotion of certain celebrity diets or products could curb some appearance-related societal pressures. School-based interventions teaching coping skills, emotional regulation, building self-esteem and challenging cognitive distortions show promise for indicated prevention.

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Screening programs can identify at-risk youth who may develop full-blown eating disorders if left untreated. Gatekeeper training enabling parents, teachers and healthcare providers to recognize early signs and behaviors associated with eating disorders can expedite treatment-seeking when problems initially emerge. Improving access to evidence-based therapies and specialized treatment services in communities is also important, especially rural areas where help may be scarce. A multi-pronged, socio-ecological approach addressing individual, familial, cultural and policy-level factors offers the best chance of curbing rising rates of eating disorders including anorexia nervosa.

Conclusions
Anorexia nervosa is a debilitating mental illness affecting millions worldwide with serious medical and psychological consequences if untreated. Genetics, personality traits, early life experiences and sociocultural pressures contribute to the onset and maintenance of the disorder. Symptoms reflect prolonged starvation and distortion of body image. Signs of anorexia should always warrant prompt medical and psychological evaluation. A team-based approach utilizing psychotherapy, nutrition counseling and stabilization of medical issues provides the optimal care model.

While anorexia can never be fully cured, early detection and comprehensive treatment significantly improve long-term prognosis and quality of life. Indicated prevention programs and policy-level advocacy aim to reshape unrealistic societal pressures driving eating disorders at their roots. Continued research into biological mechanisms, refined treatments and widespread dissemination of evidence-based approaches gives hope that more lives may be saved and suffering alleviated from this serious but treatable mental health condition.

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